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(11)

EP 3 113 760 A1

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(43) Date of publication: 11.01.2017 Bulletin 2017/02 (21) Application number: 15759285.8 (22) Date of filing: 04.03.2015

(51) International Patent Classification (IPC):  A61K 9/14(2006.01) B82Y 30/00(2011.01) A61N 2/06(2006.01) C07K 16/30(2006.01) (86) International application number: PCT/US2015/018746 (87) International publication number: WO 2015/134620 (11.09.2015 Gazette 2015/36)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA (30) Priority: 04.03.2014 US 201461947830 P (71) Applicant: Memorial Sloan Kettering Cancer Center New York, NY 10065 (US)	(72) Inventors: RENSTROM, Erik SE-26161 Landskrona (SE) STETTER, Ernst D-64342 Seeheim-Jugenheim (DE) KIRCHER, Moritz, F. New York, NY 10021 (US) KOCH, Martin DK-2500 Valby (DK) (74) Representative: Carpmaels & Ransford LLP  One Southampton Row London WC1B 5HA London WC1B 5HA (GB)