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EP 3 113 771 A1

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(43) Date of publication: 11.01.2017 Bulletin 2017/02 (21) Application number: 15758129.9 (22) Date of filing: 02.03.2015

(51) International Patent Classification (IPC):  A61K 31/404(2006.01) A61K 31/4738(2006.01) A61P 25/34(2006.01) A61K 31/55(2006.01) A61P 25/30(2006.01) (86) International application number: PCT/US2015/018356 (87) International publication number: WO 2015/134405 (11.09.2015 Gazette 2015/36)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA (30) Priority: 03.03.2014 US 201461947397 P 13.03.2014 US 201461952724 P 13.03.2014 US 201461952718 P 13.03.2014 US 201461952743 P 13.03.2014 US 201461952736 P 13.03.2014 US 201461952740 P 13.03.2014 US 201461952725 P 12.09.2014 US 201462049968 P (71) Applicant: DemeRx, Inc. Fort Lauderdale, Fl 33301 (US)

(72) Inventors: MAILLET, Emeline Fort Lauderdale, Florida 33301 (US) FRIEDHOFF, Lawrence Fort Lauderdale, Florida 33301 (US) (74) Representative: Gibson, Mark  Sagittarius IP Three Globeside Fieldhouse Lane Marlow, Buckinghamshire SL7 1HZ Marlow, Buckinghamshire SL7 1HZ (GB)