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EP 3 116 487 A1

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(43) Date of publication: 18.01.2017 Bulletin 2017/03 (21) Application number: 14722332.5 (22) Date of filing: 14.03.2014

(51) International Patent Classification (IPC):  A61K 31/137(2006.01) A61P 5/18(2006.01) A61P 43/00(2006.01) A61K 9/16(2006.01) A61P 3/14(2006.01) (86) International application number: PCT/IB2014/059787 (87) International publication number: WO 2015/136329 (17.09.2015 Gazette 2015/37)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (71) Applicants: Abdi Ibrahim Ilac Sanayi ve Ticaret Anonim Sirketi 34555 Istanbul (TR) Helm AG 20097 Hamburg (DE)	(72) Inventors: FARSHI, Farhad 34555 Istanbul (TR) DUDE, Udaya Kumar 34555 Istanbul (TR) NARSISOGLU, Nadin 34555 Istanbul (TR) GINDULLIS, Dr. Frank 20097 Hamburg (DE) YEGIN, Didem 20097 Hamburg (DE) EVERS, Dr. Britta 20097 Hamburg (DE)