(19)

(11)

EP 3 116 505 A1

(12)

(43) Date of publication: 18.01.2017 Bulletin 2017/03 (21) Application number: 15709338.6 (22) Date of filing: 09.03.2015

(51) International Patent Classification (IPC):  A61K 31/485(2006.01) A61K 47/10(2017.01) A61K 9/08(2006.01) A61P 25/04(2006.01) A61K 9/00(2006.01) A61K 47/22(2006.01) A61P 25/36(2006.01) (86) International application number: PCT/GB2015/050676 (87) International publication number: WO 2015/136253 (17.09.2015 Gazette 2015/37)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA (30) Priority: 10.03.2014 GB 201404139 (71) Applicant: Indivior UK Limited Slough Berkshire SL1 3UH (GB)	(72) Inventors: ZHOU, Mingxing Fort Collins, Colorado 80525-4417 (US) NORTON, Richard Fort Collins, Colorado 80525-4417 (US) (74) Representative: HGF Limited  1 City Walk Leeds LS11 9DX Leeds LS11 9DX (GB)