| (19) |
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(11) |
EP 3 118 211 A8 |
| (12) |
CORRECTED EUROPEAN PATENT APPLICATION |
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published in accordance with Art. 153(4) EPC |
| (15) |
Correction information: |
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Corrected version no 1 (W1 A1) |
| (48) |
Corrigendum issued on: |
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06.09.2017 Bulletin 2017/36 |
| (43) |
Date of publication: |
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18.01.2017 Bulletin 2017/03 |
| (22) |
Date of filing: 27.02.2015 |
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| (51) |
International Patent Classification (IPC):
|
| (86) |
International application number: |
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PCT/RU2015/000121 |
| (87) |
International publication number: |
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WO 2015/137846 (17.09.2015 Gazette 2015/37) |
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| (84) |
Designated Contracting States: |
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AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL
NO PL PT RO RS SE SI SK SM TR |
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Designated Extension States: |
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BA ME |
| (30) |
Priority: |
12.03.2014 RU 2014109441
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| (71) |
Applicant: Obschestvo S Ogranichennoi Otvetstvennostiyu
"Pharmenterprises" |
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Moscow 117571 (RU) |
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| (72) |
Inventors: |
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- NEBOLSIN, Vladimir Evgenievich
Istrinsky r-n
Moskovskaya obl. 143581 (RU)
- KROMOVA, Tatyana Alexandrovna
Kaluga 248010 (RU)
|
| (74) |
Representative: Hoffmann Eitle |
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Patent- und Rechtsanwälte PartmbB
Arabellastraße 30 81925 München 81925 München (DE) |
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| (54) |
AMIDE COMPOUNDS AND METHODS FOR THE PRODUCTION AND USE THEREOF |
(57) The present invention relates to medicine and includes a method for preventing and
treating diseases caused by RNA- and DNA-containing viruses, and concomitant diseases,
wherein the method comprises the use of an effective amount of compounds of general
formula I or pharmaceutically acceptable salts thereof. The invention also relates
to methods for preparing said compounds, pharmaceutical compositions for the prevention
or treatment of diseases caused by RNA- and DNA-containing viruses, said compositions
comprising an effective amount of a compound of formula I or a pharmaceutically acceptable
salt thereof. The invention addresses the object of providing a novel agent effective
in the treatment of diseases caused by an RNA-containing virus belonging to the Enterovirus,
Metapneumovirus, Pneumovirus, Respirovirus, or Alfa-coronavirus genus, and/or by a
DNA-containing virus belonging to the Adenoviridae and/or Herpesviridae family, and
in the prevention and treatment of asthma exacerbation, chronic obstructive pulmonary
disease, mucoviscidosis, conjunctivitis, gastroenteritis, hepatitis, myocarditis;
in the prevention and treatment of rhinorrhea, acute and infectious rhinitis, pharyngitis,
nasopharyngitis, tonsillitis, laryngitis, laryngotracheitis, laryngotracheobronchitis,
bronchitis, bronchiolitis, pneumonia, or airway obstructive syndrome.