(19)
(11) EP 3 122 799 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
11.03.2020 Bulletin 2020/11

(45) Mention of the grant of the patent:
15.01.2020 Bulletin 2020/03

(21) Application number: 15715932.8

(22) Date of filing: 25.03.2015
(51) International Patent Classification (IPC): 
C08G 65/30(2006.01)
C07K 16/00(2006.01)
 C12N 5/00(2006.01)
(86) International application number:
PCT/US2015/022592
(87) International publication number:
WO 2015/148736 (01.10.2015 Gazette 2015/39)

(54)

METHODS OF PREPARING A POLOXAMER FOR USE IN CELL CULTURE MEDIUM

VERFAHREN ZUR HERSTELLUNG VON POLOXAMER ZUR VERWENDUNG BEI ZELLKULTURMEDIUM

PROCÉDÉ DE PRÉPARATION DE POLOXAMÈRE POUR UNE UTILISATION DANS MILIEU DE CULTURE CELLULAIRE

(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 25.03.2014 US 201461970281 P

(43) Date of publication of application:
01.02.2017 Bulletin 2017/05

(60) Divisional application:
20151556.6

(73) Proprietor: F. Hoffmann-La Roche AG
4070 Basel (CH)

(72) Inventors:
  • VISSVESVARAN, Ganesh, Prasadh
    South San Francisco, CA 94080 (US)
  • KISS, Robert, David
    South San Francisco, CA 94080 (US)
  • MEIER, Steven, J.
    South San Francisco, CA 94080 (US)
  • KWON, Inchan
    Charlottesville, VA 22911 (US)
  • CALHOUN, Kara
    South San Francisco, CA 94080 (US)
  • WINCHESTER, Kate
    South San Francisco, CA 94080 (US)
  • ADAMS, Amelia
    South San Francisco, CA 94080 (US)
  • GLENN, Marion
    South San Francisco, CA 94080 (US)
  • KOENIG, Stefan
    South San Francisco, CA 94080 (US)
  • DEESE, Alan
    South San Francisco, CA 94080 (US)

(74) Representative: Klaus, Michaela 
F. Hoffmann-La Roche AG Patent Department Grenzacherstrasse 124
4070 Basel
4070 Basel (CH)


(56) References cited: : 
EP-B1- 1 661 558
 WO-A2-2004/071452
   
  • YONG C S ET AL: "Enhanced anti-tumor activity and alleviated hepatotoxicity of clotrimazole-loaded suppository using poloxamer-propylene glycol gel", INTERNATIONAL JOURNAL OF PHARMACEUTICS, ELSEVIER BV, NL, vol. 321, no. 1-2, 14 September 2006 (2006-09-14), pages 56-61, XP027972634, ISSN: 0378-5173 [retrieved on 2006-09-14]
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).