(19)
(11) EP 3 125 929 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
27.12.2023 Bulletin 2023/52

(45) Mention of the grant of the patent:
01.11.2023 Bulletin 2023/44

(21) Application number: 15713532.8

(22) Date of filing: 02.04.2015
(51) International Patent Classification (IPC): 
A61K 39/002(2006.01)
A61K 39/29(2006.01)
A61K 39/015(2006.01)
A61K 39/39(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 39/04; A61K 2039/545; A61K 2039/55572; A61K 2039/55577; A61P 31/06; A61P 33/06; A61P 37/04; Y02A 50/30
(86) International application number:
PCT/EP2015/057424
(87) International publication number:
WO 2015/150568 (08.10.2015 Gazette 2015/40)

(54)

NOVEL METHODS FOR INDUCING AN IMMUNE RESPONSE

NEUE VERFAHREN ZUR IMMUNISIERUNG

METHODES NOUVELLES POUR INDUIRE DES REPONSES IMMUNITAIRES


(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME

(30) Priority: 02.04.2014 GB 201405921

(43) Date of publication of application:
08.02.2017 Bulletin 2017/06

(73) Proprietor: GlaxoSmithKline Biologicals S.A.
1330 Rixensart (BE)

(72) Inventors:
  • BALLOU, William Ripley Jr.
    B-1330 Rixensart (BE)
  • DIDIERLAURENT, Arnaud, Michel
    B-1330 Rixensart (BE)
  • VAN DER MOST, Robbert, Gerrit
    B-1330 Rixensart (BE)

(74) Representative: J A Kemp LLP 
80 Turnmill Street
London EC1M 5QU
London EC1M 5QU (GB)


(56) References cited: : 
   
  • STOUTE J A ET AL: "A PRELIMINARY EVALUATION OF A RECOMBINANT CIRCUMSPOROZOITE PROTEIN VACCINE AGAINST PLASMODIUM FALCIPARUM MALARIA", NEW ENGLAND JOURNAL OF MEDICINE, MASSACHUSETTS MEDICAL SOCIETY, US, vol. 336, no. 2, 9 January 1997 (1997-01-09), pages 86-91, XP000990284, ISSN: 0028-4793, DOI: 10.1056/NEJM199701093360202 cited in the application
  • HILL ADRIAN V S: "Vaccines against malaria", PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON. SERIES B: BIOLOGICAL SCIENCES, ROYAL SOCIETY OF LONDON, LONDON, GB, vol. 366, no. 1579, 12 October 2011 (2011-10-12), pages 2806-2814, XP002700406, ISSN: 0080-4622, DOI: 10.1098/RSTB.2011.0091
  • W. R. BALLOU: "The development of the RTS,S malaria vaccine candidate: challenges and lessons", PARASITE IMMUNOLOGY, vol. 31, no. 9, 1 September 2009 (2009-09-01), pages 492-500, XP55208451, ISSN: 0141-9838, DOI: 10.1111/j.1365-3024.2009.01143.x
  • STOUTE J A ET AL: "LONG-TERM EFFICACY AND IMMUNE RESPONSES FOLLOWING IMMUNIZATION WITH THE RTS,S MALARIA VACCINE", JOURNAL OF INFECTIOUS DISEASES. JID, UNIVERSITY OF CHICAGO PRESS, CHICAGO, IL, vol. 178, no. 4, 1 October 1998 (1998-10-01), pages 1139-1144, XP008046110, ISSN: 0022-1899, DOI: 10.1086/515657
  • ELENA MATA ET AL: "Malaria Vaccine Adjuvants: Latest Update and Challenges in Preclinical and Clinical Research", BIOMED RESEARCH INTERNATIONAL, vol. 6, no. 5, 1 January 2013 (2013-01-01) , pages 599-19, XP55208483, ISSN: 2314-6133, DOI: 10.1016/j.ijpharm.2008.08.039
  • L. C. PAOLETTI ET AL: "Effects of Alum Adjuvant or a Booster Dose on Immunogenicity during Clinical Trials of Group B Streptococcal Type III Conjugate Vaccines", INFECTION AND IMMUNITY, vol. 69, no. 11, 1 November 2001 (2001-11-01), pages 6696-6701, XP55208551, ISSN: 0019-9567, DOI: 10.1128/IAI.69.11.6696-6701.2001
  • GIOVANNI GABUTTI ET AL: "Booster Vaccination: The Role of Reduced Antigen Content Vaccines as a Preschool Booster", BIOMED RESEARCH INTERNATIONAL, vol. 60, no. 1, 1 January 2014 (2014-01-01), pages 13-10, XP55192849, ISSN: 2314-6133, DOI: 10.4103/0974-777X.77298
   
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