ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESILTLVFIROMKCYALTRBGCZEEHUPLSK..HRIS..MTNORS..SM..................*JBDM Ver 1.7.2 (20 November 2019) - 2999001/03129473CORRECTED EUROPEAN PATENT SPECIFICATIONB8B120201223W173deBibliographieenBibliographyfrBibliographieEP15715273.7201504102016110720170807enenen20147020920140411DK2020122320205220170215201707202003182020122019112120200618BG20200318CZ20200318EE20200318FI20200619GR20200318HR20200718IS20200318LT20200318LV20200318NL20200618NO20200812PT20200318RO20200318RS20200318SE20200318SK20200318SM20201223202052C12N 5/10 20060101AFI20151019BHEP A61K 35/12 20150101ALI20151019BHEP A61K 35/14 20150101ALI20151019BHEP deVERFAHREN ZUR ERZEUGUNG VON IMMUNZELLEN, DIE GEGEN EINE ARGININ- UND/ODER TRYPTOPHANVERARMTE MIKROUMGEBUNG RESISTENT SINDenMETHOD FOR GENERATING IMMUNE CELLS RESISTANT TO ARGININE AND/OR TRYPTOPHAN DEPLETED MICROENVIRONMENTfrPROCÉDÉ PERMETTANT LA PRODUCTION DE CELLULES IMMUNITAIRES RÉSISTANTES À UN MICROENVIRONNEMENT APPAUVRI EN ARGININE ET/OU EN TRYPTOPHANEWO-A1-2013/176916WO-A1-2014/184744WO-A1-2014/191128US-A1- 2011 058 957K MORROW ET AL: "Anti-leukemic mechanisms of pegylated arginase I in acute lymphoblastic T-cell leukemia", LEUKEMIA, vol. 27, no. 3, 28 August 2012 (2012-08-28), pages 569-577, XP055137415, ISSN: 0887-6924, DOI: 10.1038/leu.2012.247DAVID H MUNN ET AL: "GCN2 kinase in T cells mediates proliferative arrest and energy induction in response to indoleamine 2,3-dioxygenase", IMMUNITY, CELL PRESS, US, vol. 22, no. 5, 1 May 2005 (2005-05-01), pages 633-642, XP008129338, ISSN: 1074-7613, DOI: 10.1016/J.IMMUNI.2005.03.013FALLARINO FRANCESCA ET AL: "The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells", JOURNAL OF IMMUNOLOGY, vol. 176, no. 11, June 2006 (2006-06), pages 6752-6761, XP002729121, ISSN: 0022-1767NABILA SEDDIKI ET AL: "The microRNA-9/B-lymphocyte-induced maturation protein-1/IL-2 axis is differentially regulated in progressive HIV infection", EUROPEAN JOURNAL OF IMMUNOLOGY, vol. 43, no. 2, 1 February 2013 (2013-02-01), pages 510-520, XP055084710, ISSN: 0014-2980, DOI: 10.1002/eji.201242695SALEHI SOOFIA ET AL: "B Lymphocyte-Induced Maturation Protein-1 Contributes to Intestinal Mucosa Homeostasis by Limiting the Number of IL-17-Producing CD4(+) T Cells", JOURNAL OF IMMUNOLOGY, vol. 189, no. 12, December 2012 (2012-12), pages 5682-5693, XP002729122, ISSN: 0022-1767POIROT, Laurent10 rue de la réunionF-75020 ParisFRSIMON, Mathieu76 avenue MozartF-75016 ParisFRCellectis101284761P81401593EP008, rue de la Croix Jarry75013 ParisFRZacco Denmark A/S101463545Arne Jacobsens Allé 152300 Copenhagen SDKALATBEBGCHCYCZDEDKEEESFIFRGBGRHRHUIEISITLILTLULVMCMKMTNLNOPLPTRORSSESISKSMTREP201505786520150410enWO201515534120151015201541