(19)
(11) EP 3 140 308 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
28.06.2023 Bulletin 2023/26

(45) Mention of the grant of the patent:
24.05.2023 Bulletin 2023/21

(21) Application number: 15726407.8

(22) Date of filing: 28.04.2015
(51) International Patent Classification (IPC): 
C07D 489/12(2006.01)
 C07D 489/08(2006.01)
(52) Cooperative Patent Classification (CPC):
C07D 489/08; C07D 489/12
(86) International application number:
PCT/US2015/027912
(87) International publication number:
WO 2015/171354 (12.11.2015 Gazette 2015/45)

(54)

PROCESS FOR THE PREPARATION OF OPIOID COMPOUNDS

VERFAHREN ZUR HERSTELLUNG VON OPIOIDVERBINDUNGEN

PROCÉDÉ DE PRÉPARATION DE COMPOSÉS OPIOÏDES

(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 05.05.2014 US 201461988523 P
17.04.2015 US 201514689712

(43) Date of publication of application:
15.03.2017 Bulletin 2017/11

(73) Proprietor: Noramco, LLC
Wilmington, DE 19801 (US)

(72) Inventors:
  • CONZA, Matteo
    8240 Schaffhausen (CH)
  • LELLEK, Vit
    8193 Eglisau (CH)
  • ZINSER, Hartmut
    8200 Schaffhausen (CH)

(74) Representative: Boult Wade Tennant LLP 
Salisbury Square House 8 Salisbury Square
London EC4Y 8AP
London EC4Y 8AP (GB)


(56) References cited: : 
WO-A1-2008/137672
WO-A2-2013/050748
US-A1- 2010 081 819
US-A1- 2012 283 443
 WO-A2-2008/064351
US-A1- 2010 036 128
US-A1- 2011 313 163
   
  • MACHARA A ET AL: "Improved Synthesis of Buprenorphine from Thebaine and/or Oripavine via Palladium-Catalyzed N-Demethylation/Acylation and/or Concomitant O-Demethylation", ADVANCED SYNTHESIS AND CATALYSIS, WILEY, WEINHEIM, DE, vol. 354, no. 4, 1 January 2012 (2012-01-01), pages 613-626, XP009177295, ISSN: 1615-4169
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).