(19)
(11) EP 3 140 323 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
23.05.2018 Bulletin 2018/21

(45) Mention of the grant of the patent:
04.04.2018 Bulletin 2018/14

(21) Application number: 15720008.0

(22) Date of filing: 22.04.2015
(51) International Patent Classification (IPC): 
G01N 33/80(2006.01)
G01N 33/564(2006.01)
C07K 16/28(2006.01)
(86) International application number:
PCT/EP2015/058738
(87) International publication number:
WO 2015/169602 (12.11.2015 Gazette 2015/45)

(54)

METHOD FOR THE SEROLOGICAL DIAGNOSIS OF RHEUMATOID ARTHRITIS.

VERFAHREN ZUR SEROLOGISCHEN DIAGNOSE VON RHEUMATOIDER ARTHRITIS

PROCÉDÉ DE DIAGNOSTIC SÉROLOGIQUE DE LA POLYARTHRITE RHUMATOÏDE


(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 05.05.2014 EP 14166985

(43) Date of publication of application:
15.03.2017 Bulletin 2017/11

(73) Proprietor: Novio TH B.V.
6536 CL Nijmegen (NL)

(72) Inventor:
  • SALDEN, Martinus Hubertus Leonardus
    NL-6536 CL Nijmegen (NL)

(74) Representative: Life Science Patents B.V. 
Oxfordlaan 55
6229 EV Maastricht
6229 EV Maastricht (NL)


(56) References cited: : 
WO-A1-2009/115612
WO-A2-03/050542
   
  • JOYCE JBC VAN BEERS ET AL: "ACPA fine-specificity profiles in early rheumatoid arthritis patients do not correlate with clinical features at baseline or with disease progression", ARTHRITIS RESEARCH AND THERAPY, BIOMED CENTRAL, LONDON, GB, vol. 15, no. 5, 1 October 2013 (2013-10-01), page R140, XP021165639, ISSN: 1478-6354, DOI: 10.1186/AR4322
  • WALTHER J. VAN VENROOIJ ET AL: "Anti-CCP antibodies: the past, the present and the future", NATURE REVIEWS RHEUMATOLOGY, vol. 7, no. 7, 7 June 2011 (2011-06-07), pages 391-398, XP055145475, ISSN: 1759-4790, DOI: 10.1038/nrrheum.2011.76
  • SCHELLEKENS GG ET AL: "Citrulline is an essential constituent of antigenic determinant recognized by rheumatoid arthritis-specific autoantibodies", JOURNAL OF CLINICAL INVESTIGATION, AMERICAN SOCIETY FOR CLINICAL INVESTIGATION, US, vol. 101, no. 1, 1 January 1998 (1998-01-01), pages 273-281, XP002108877, ISSN: 0021-9738, DOI: 10.1172/JCI1316
  • CATIMEL B ET AL: "Kinetics of the autologous red cell agglutination test", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 165, no. 2, 15 October 1993 (1993-10-15), pages 183-192, XP023974634, ISSN: 0022-1759, DOI: 10.1016/0022-1759(93)90344-7 [retrieved on 1993-10-15]
   
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