(19)
(11) EP 3 145 935 A1

(12)

(43) Date of publication:
29.03.2017 Bulletin 2017/13

(21) Application number: 16727341.6

(22) Date of filing: 23.05.2016
(51) International Patent Classification (IPC): 
C07D 498/04(2006.01)
A61K 31/423(2006.01)
A61P 25/30(2006.01)
A61P 25/28(2006.01)
 C07D 263/56(2006.01)
A61K 31/424(2006.01)
A61P 3/04(2006.01)
(86) International application number:
PCT/EP2016/061620
(87) International publication number:
WO 2016/188972 (01.12.2016 Gazette 2016/48)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA MD

(30) Priority: 22.05.2015 EP 15169052

(71) Applicant: Universiteit Leiden
2311 EZ Leiden (NL)

(72) Inventors:
  • VAN DER STELT, Mario
    2333 CC Leiden (NL)
  • JANSSEN, Freek
    2333 CC Leiden (NL)
  • BAGGELAAR, Marc
    2333 CC Leiden (NL)
  • HUMMEL, Jessica
    2333 CC Leiden (NL)

(74) Representative: Arth, Hans-Lothar 
ABK Patent Attorneys Jasminweg 9
14052 Berlin
14052 Berlin (DE)

   


(54) PHARMACEUTICALLY ACTIVE COMPOUNDS AS DAG-LIPASE INHIBITORS