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(11)

EP 3 151 771 A1

(12)

(43) Date of publication: 12.04.2017 Bulletin 2017/15 (21) Application number: 15726484.7 (22) Date of filing: 20.05.2015

(51) International Patent Classification (IPC):  A61B 18/14(2006.01) A61B 90/00(2016.01) A61M 25/00(2006.01) (86) International application number: PCT/US2015/031660 (87) International publication number: WO 2015/187361 (10.12.2015 Gazette 2015/49)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA (30) Priority: 07.06.2014 US 201462009223 P 07.06.2014 US 201462009222 P 09.05.2015 US 201514708209 09.05.2015 US 201514708210 (71) Applicant: Mederi Therapeutics, Inc. Norwalk, CT 06854 (US)

(72) Inventors: SHIKHMAN, Oleg Trumbull, CT 06611 (US) GREEN, Ronald L. Bethel, CT 06801 (US) RADZIUNAS, Jeffrey Wallingford, CT 06492 (US) (74) Representative: Jackson, Derek Charles  Derek Jackson Associates The Old Yard Lower Town Claines, Worcester WR3 7RY Claines, Worcester WR3 7RY (GB)