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(11)

EP 3 155 087 A2

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(88) Date of publication A3: 26.04.2012 (43) Date of publication: 19.04.2017 Bulletin 2017/16 (21) Application number: 11807444.2 (22) Date of filing: 13.07.2011

(51) International Patent Classification (IPC):  C12M 3/02(2006.01) C12N 5/09(2010.01) G01N 33/50(2006.01) C12M 1/24(2006.01) C12Q 1/04(2006.01) G01N 33/15(2006.01) (86) International application number: PCT/US2011/043837 (87) International publication number: WO 2012/009425 (19.01.2012 Gazette 2012/03)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 13.07.2010 US 363831 P (71) Applicants: NanoPharmaceuticals LLC Rensselaer, NY 12144 (US) Lin, Hung-Yun Schenectady NY 12303 (US) Drusano, George Latham, NY 12110 (US) Louie, Arnold Selkirk, NY 12158 (US) Davis, Paul J. West Sand Lake NY 12196 (US)

(72) Inventors: LIN, Hung-Yun Schenectady, NY 12303 (US) DRUSANO, George Latham, NY 12110 (US) LOUIE, Arnold Selkirk, NY 12158 (US) DAVIS, Paul, J. West Sand Lake, NY 12196 (US) (74) Representative: Michalski Hüttermann & Partner Patentanwälte mbB  Speditionstraße 21 40221 Düsseldorf 40221 Düsseldorf (DE)