(19)
(11) EP 3 155 098 A1

(12)

(43) Date of publication:
19.04.2017 Bulletin 2017/16

(21) Application number: 15807028.4

(22) Date of filing: 11.06.2015
(51) International Patent Classification (IPC): 
C12N 15/09(2006.01)
C12N 9/10(2006.01)
C07K 14/755(2006.01)
A61P 7/00(2006.01)
C12N 15/12(2006.01)
C12N 9/16(2006.01)
A61K 48/00(2006.01)
(86) International application number:
PCT/US2015/035399
(87) International publication number:
WO 2015/191899 (17.12.2015 Gazette 2015/50)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA

(30) Priority: 11.06.2014 US 201462011019 P

(71) Applicant: Howard, Tom E.
Redondo Beach, California 90278 (US)

(72) Inventor:
  • Howard, Tom E.
    Redondo Beach, California 90278 (US)

(74) Representative: Thom, Russell 
Murgitroyd & Company Scotland House 165-169 Scotland Street
Glasgow G5 8PL
Glasgow G5 8PL (GB)

   


(54) FACTOR VIII MUTATION REPAIR AND TOLERANCE INDUCTION AND RELATED CDNAs, COMPOSITIONS, METHODS AND SYSTEMS