ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESILTLVFIROMKCY..TRBGCZEEHUPLSK..HRIS..MTNO....SM..................JBDM Ver 0.1.63 (23 May 2017) - 2999001/03156494CORRECTED EUROPEAN PATENT SPECIFICATIONB8B120180919W173deBibliographieenBibliographyfrBibliographieEP16200237.22009120320161123enenen200985 P20081204US205970 P20090126US263904 P20091124US2018091920183820170419201716201804252018172018030820180919201838C12N 15/85 20060101AFI20170316BHEP deGENOMÄNDERUNG BEI RATTEN MITHILFE VON ZINK-FINGER-NUKLEASENenGENOME EDITING IN RATS USING ZINC-FINGER NUCLEASESfrÉDITION DE GÉNOME CHEZ DES RATS AU MOYEN DE NUCLÉASES EN DOIGT DE ZINCEP-A1- 1 348 335WO-A1-2008/151081WO-A2-03/080809WO-A2-03/087341US-A1- 2009 205 083MILLER JEFFREY C ET AL: "An improved zinc-finger nuclease architecture for highly specific genome editing", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, vol. 25, no. 7, 1 July 2007 (2007-07-01), pages 778-785, XP002465119, ISSN: 1087-0156, DOI: 10.1038/NBT1319URNOV F D ET AL: "Highly efficient endogenous human gene correction using designed zinc-finger nucleases", NATURE: INTERNATIONAL WEEKLY JOURNAL OF SCIENCE, NATURE PUBLISHING GROUP, UNITED KINGDOM, vol. 435, no. 7042, 2 June 2005 (2005-06-02), pages 646-651, XP002411069, ISSN: 0028-0836, DOI: 10.1038/NATURE03556PORTEUS M H ET AL: "GENE TARGETING USING ZINC FINGER NUCLEASES", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, vol. 23, no. 8, 1 August 2005 (2005-08-01) , pages 967-973, XP002467422, ISSN: 1087-0156, DOI: 10.1038/NBT1125DOYON Y ET AL: "Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases", NATURE BIOTECHNOLOGY, GALE GROUP INC, US, vol. 26, no. 6, 1 June 2008 (2008-06-01), pages 702-708, XP002512110, ISSN: 1087-0156, DOI: 10.1038/NBT1409 [retrieved on 2008-05-25]MENG XIANGDONG ET AL: "Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases", NATURE BIOTECHNOLOGY, GALE GROUP INC, US, vol. 26, no. 6, 1 June 2008 (2008-06-01), pages 695-701, XP002512111, ISSN: 1087-0156, DOI: 10.1038/NBT1398 [retrieved on 2008-05-25]09830727.5235236920091203CUI, Xiaoxia1231 Craig RoadSt. Louis, MO 63146USGEURTS, Aron M.13370 Sunburst Ct.New Berlin, WI 53151USURNOV, Fyodorc/o Sangamo Therapeutics, Inc. Point Richmond Tech Center 501 Canal Boulevard, Suite A100Richmond, CA 94804USSangamo Therapeutics, Inc.10165542650975PEPWO1Point Richmond Tech Center 501 Canal Blvd., Suite A100Richmond, CA 94804USSigma-Aldrich Co.10175876850975PEPWO13050 Spruce StreetSt. Louis, MO 63103USWeickmann & Weickmann PartmbB101515769Postfach 860 82081635 MünchenDEATBEBGCHCYCZDEDKEEESFIFRGBGRHRHUIEISITLILTLULVMCMKMTNLNOPLPTROSESISKSMTR