(19)
(11) EP 3 170 834 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
23.03.2022 Bulletin 2022/12

(45) Mention of the grant of the patent:
09.02.2022 Bulletin 2022/06

(21) Application number: 16202285.9

(22) Date of filing: 19.06.2009
(51) International Patent Classification (IPC): 
C07H 19/01(2006.01)
C07D 493/10(2006.01)
 C07H 1/00(2006.01)
A61P 3/10(2006.01)
(52) Cooperative Patent Classification (CPC):
C07D 493/10; C07H 1/00; C07H 19/01; A61P 3/10

(54)

CRYSTALLINE FORMS OF (1S,3'R,4'S,5'S,6'R)-6-[(4-ETHYLPHENYL)METHYL]-3',4',5',6'-TETRAHYDRO-6'-(HYDROXYMETHYL)SPIRO[ISOBENZOFURAN-1(3H) 2'-[2H]PYRAN]-3',4',5'-TRIOL

KRISTALLINE FORMEN VON (1S,3'R,4'S,5'S,6'R)-6-[(4-ETHYLPHENYL)METHYL]-3',4',5',6'-TETRAHYDRO-6'-(HYDROXYMETHYL)SPIRO[ISOBENZOFURAN-1(3H) 2'-[2H]PYRAN]-3',4',5'-TRIOL

FORMES CRISTALLINES DE 2'-[2H]PYRAN]-3',4',5'-TRIOL DE (1S,3'R,4'S,5'S,6'R)-6-[(4-ETHYLPHENYL)METHYL]-3',4',5',6'-TETRAHYDRO-6'-(HYDROXYMETHYL)SPIRO[ISOBENZOFURAN-1(3H)

(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR
Designated Extension States:
AL BA RS

(30) Priority: 20.06.2008 JP 2008162073

(43) Date of publication of application:
24.05.2017 Bulletin 2017/21

(60) Divisional application:
22155547.7

(62) Application number of the earlier application in accordance with Art. 76 EPC:
09766724.0 / 2308886

(73) Proprietor: Chugai Seiyaku Kabushiki Kaisha
Kita-ku Tokyo 115-8543 (JP)

(72) Inventors:
  • MURAKATA, Masatoshi
    Tokyo 115-8543 (JP)
  • IKEDA, Takuma
    Tokyo 115-8543 (JP)
  • KIMURA, Nobuaki
    Tokyo 115-8543 (JP)
  • KAWASE, Akira
    Tokyo 155-8543 (JP)
  • NAGASE, Masahiro
    Tokyo 115-8543 (JP)
  • YAMAMOTO, Keisuke
    Gotenba-shi Shizuoka 412-8513 (JP)
  • TAKATA, Noriyuki
    Gotenba-shi Shizioka 412-8513 (JP)
  • YOSHIZAKI, Shinichi
    Gotenba-shi Shizuoka 412-8513 (JP)
  • TAKANO, Koji
    Gotenba-shi Shizuoka 412-8513 (JP)

(74) Representative: Vossius & Partner Patentanwälte Rechtsanwälte mbB 
Siebertstrasse 3
81675 München
81675 München (DE)


(56) References cited: : 
EP-A1- 1 852 439
 WO-A2-2007/140191
   
  • CAIRA M R: "CRYSTALLINE POLYMORPHISM OF ORGANIC COMPOUNDS", TOPICS IN CURRENT CHEMISTRY, SPRINGER, BERLIN, DE, vol. 198, 1 January 1998 (1998-01-01), pages 163-208, XP001156954, ISSN: 0340-1022, DOI: 10.1007/3-540-69178-2_5
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).