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EP 3 180 365 A1

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(43) Date of publication: 21.06.2017 Bulletin 2017/25 (21) Application number: 15832619.9 (22) Date of filing: 14.08.2015

(51) International Patent Classification (IPC):  C07K 19/00(2006.01) C07K 4/00(2006.01) A61K 38/17(2006.01) A61P 37/00(2006.01) C07K 14/46(2006.01) C12N 15/63(2006.01) A61P 35/00(2006.01) (86) International application number: PCT/AU2015/000487 (87) International publication number: WO 2016/023072 (18.02.2016 Gazette 2016/07)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA (30) Priority: 15.08.2014 AU 2014903189 (71) Applicants: Monash University Melbourne, Victoria 3800 (AU) LA TROBE UNIVERSITY Bundoora, VIC 3086 (AU) Peptides International, Inc. Louisville, Kentucky 40299 (US) Baylor College of Medicine Houston, TX 77030 (US)

(72) Inventors: NORTON, Raymond, S Rosanna, Victoria 3084 (AU) CHANG, Shih, Chieh Singapore 670422 (SG) PENNINGTON, Michael, W Shelbyville, Kentucky 40065 (US) BEETON, Christine Pearland, TX 77584 (US) SMITH, Brian, J. Sunbury, Victoria 3429 (AU) (74) Representative: Gill Jennings & Every LLP  The Broadgate Tower 20 Primrose Street London EC2A 2ES London EC2A 2ES (GB)