ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESILTLVFIROMKCYALTRBGCZEEHUPLSKBAHRIS..MTNORSMESMMA....MD..........JBDM Ver 0.1.63 (23 May 2017) - 1999001/0Amended claims in accordance with Rule 137(2) EPC.3182366CORRECTED EUROPEAN PATENT APPLICATIONA8A120171129W172deBibliographieenBibliographyfrBibliographieEP15200864.520151217enenen201711292017482017062120172520171129201748G06T 7/00 20170101AFI20160630BHEP deEIGENSCHAFTSMESSUNG AUF EINER BIOLOGISCHEN GEWEBEPROBEenPROPERTY MEASUREMENT ON A BIOLOGICAL TISSUE SAMPLEfrMESURE DE PROPRIÉTÉ SUR UN ÉCHANTILLON DE TISSU BIOLOGIQUE1Leibniz-Institut für Photonische Technologien e.V.101477143L7790-EP / AOAlbert-Einstein-Strasse 907745 JenaDEFriedrich-Schiller-Universität Jena100125793L7790-EP / AOFürstengraben 107743 JenaDEPopp, JürgenAm Wiesenbach 3007751 Jena-KunitzDEBocklitz, ThomasArvid-Harnack-Str.907743 JenaDEChernavskaia, OlgaZiegesarstr.707747 JenaDEMeyer, TobiasHornstr.407745 JenaDEMaiwald Patentanwalts GmbH100061181Elisenhof Elisenstrasse 380335 MünchenDEALATBEBGCHCYCZDEDKEEESFIFRGBGRHRHUIEISITLILTLULVMCMKMTNLNOPLPTRORSSESISKSMTRBAMEMAMD20170621201725

A method for determining the presence or absence of a local and/or global property (6) of a biological tissue sample (1), comprising:
• acquiring (100, 110, 120, 130) an image (2) of the sample (1);
• searching (200) the image (2) for the presence of each feature (30-39) that is contained in a pre-defined set (3) of features (30-39), and assigning (250), to at least one feature (30-39), a corresponding pronunciation index (40-49) that is a measure of how pronounced each feature (30-39) is in the image or parts of it (2),
• computing (300) at least one discriminant value (5), e.g. a linear discriminant value, LD, that is a function of the weighted pronunciation indices (40-49), wherein the weight (50-59) of each pronunciation index (40-49) is a measure for the relevance of the corresponding feature (30-39) with respect to the property (6), and
• determining (400) that the property (6) is present or absent in the sample (1) or part of it depending on whether the discriminant value exceeds a pre-defined and/or optimized threshold (7) or not.