(19)

(11)

EP 3 188 718 A1

(12)

(43) Date of publication: 12.07.2017 Bulletin 2017/28 (21) Application number: 15767000.1 (22) Date of filing: 08.09.2015

(51) International Patent Classification (IPC):  A61K 9/20(2006.01) A61K 31/4545(2006.01) A61K 47/36(2006.01) A61K 47/12(2006.01) A61K 31/135(2006.01) A61K 47/26(2006.01) A61K 47/42(2017.01) (86) International application number: PCT/US2015/049000 (87) International publication number: WO 2016/037189 (10.03.2016 Gazette 2016/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA (30) Priority: 05.09.2014 US 201462046712 P 12.02.2015 US 201562115618 P 19.02.2015 US 201514626897 (71) Applicant: Santa Cruz Pharmaceuticals Inc. Santa Cruz, California 95060 (US)	(72) Inventors: WESTHUSING, Michael T. Alamo, California 94507 (US) BAI, Yong Santa Cruz, California 95060 (US) MEDRI, Mario W. Miami Lakes, Florida 33016 (US) (74) Representative: Bridle, Andrew Barry  Bridle Intellectual Property Ltd 6F Thomas Way Lakeview International Business Park Canterbury Kent CT3 4JZ Canterbury Kent CT3 4JZ (GB)