(19)
(11) EP 3 191 823 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
08.01.2020 Bulletin 2020/02

(45) Mention of the grant of the patent:
20.11.2019 Bulletin 2019/47

(21) Application number: 15760442.2

(22) Date of filing: 08.09.2015
(51) International Patent Classification (IPC): 
G01N 24/08(2006.01)
G01R 33/465(2006.01)
 G01R 33/46(2006.01)
G01R 33/28(2006.01)
(86) International application number:
PCT/EP2015/070457
(87) International publication number:
WO 2016/038013 (17.03.2016 Gazette 2016/11)

(54)

SABRE NMR ANALYSIS METHOD

SABRE-NMR-ANALYSEVERFAHREN

PROCÉDÉ D'ANALYSE RMN SABRE

(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 08.09.2014 NL 2013436
24.09.2014 EP 14186272
31.08.2015 NL 2015380

(43) Date of publication of application:
19.07.2017 Bulletin 2017/29

(73) Proprietor: Stichting Katholieke Universiteit
6525 EZ Nijmegen (NL)

(72) Inventors:
  • RUTJES, Floris Petrus Johannes Theodorus
    NL-6500 HC Nijmegen (NL)
  • FEITERS, Martinus Christiaan
    NL-6500 HC Nijmegen (NL)
  • VAN WEERDENBURG, Bram Johannes Arnoldus
    NL-6500 HC Nijmegen (NL)
  • ESHUIS, Nan
    NL-6500 HC Nijmegen (NL)
  • HERMKENS, Niels Koen Jan
    NL-6500 HC Nijmegen (NL)
  • TESSARI, Marco
    NL-6500 HC Nijmegen (NL)

(74) Representative: EDP Patent Attorneys B.V. 
Bronland 12-E
6708 WH Wageningen
6708 WH Wageningen (NL)


(56) References cited: : 
   
  • WEVERS RON A ET AL: "1H-NMR spectroscopy of body fluids: Inborn errors of purine and pyrimidine metabolism", CLINICAL CHEMISTRY, vol. 45, no. 4, April 1999 (1999-04), pages 539-548, XP055227883, ISSN: 0009-9147
  • NAN ESHUIS ET AL: "Toward Nanomolar Detection by NMR Through SABRE Hyperpolarization", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 136, no. 7, 29 January 2014 (2014-01-29), pages 2695-2698, XP055167860, ISSN: 0002-7863, DOI: 10.1021/ja412994k cited in the application
  • SANTOSH KUMAR BHARTI ET AL: "Quantitative 1H NMR spectroscopy", TRAC TRENDS IN ANALYTICAL CHEMISTRY, vol. 35, 1 May 2012 (2012-05-01), pages 5-26, XP055167863, ISSN: 0165-9936, DOI: 10.1016/j.trac.2012.02.007
  • MARCONE M F ET AL: "Diverse food-based applications of nuclear magnetic resonance (NMR) technology", FOOD RESEARCH INTERNATIONAL MAY 2013 ELSEVIER LTD GBR, vol. 51, no. 2, May 2013 (2013-05), pages 729-747, XP055227884, DOI: 10.1016/J.FOODRES.2012.12.046
  • GLÖGGLER STEFAN ET AL: "Para-hydrogen perspectives in hyperpolarized NMR", JOURNAL OF MAGNETIC RESONANCE, vol. 235, 24 July 2013 (2013-07-24), pages 130-142, XP028713301, ISSN: 1090-7807, DOI: 10.1016/J.JMR.2013.07.010
   
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