COMBINATIONS OF LOW, IMMUNE ENHANCING. DOSES OF MTOR INHIBITORS AND CARS - Patent 3193915

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EP 3 193 915 A1

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(43)	Date of publication:
	26.07.2017 Bulletin 2017/30

(21)	Application number: 15753232.6

(22)	Date of filing: 21.07.2015

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International Patent Classification (IPC):

A61K 39/00^(2006.01)

A61K 31/4745^(2006.01)

(86)	International application number:
	PCT/US2015/041330

(87)	International publication number:
	WO 2016/014530 (28.01.2016 Gazette 2016/04)

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
	Designated Extension States:
	BA ME
	Designated Validation States:
	MA

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Priority:

21.07.2014 US 201462027152 P
06.11.2014 US 201462076197 P
20.05.2015 US 201562164357 P

(71)	Applicants:
	Novartis AG 4056 Basel (CH) The Trustees of The University of Pennsylvania Philadelphia, PA 19104 (US)

(72)	Inventors:
	BROGDON, Jennifer Cambridge, MA 02139 (US) GLASS, David Cambridge, MA 02139 (US) MANNICK, Joan Cambridge, MA 02139 (US) MILONE, Michael, C. Cherry Hill, NJ 08002 (US) MURPHY, Leon Cambridge, MA 02139 (US)

(74)	Representative: Wilding, James Roger et al
	Mathys & Squire LLP The Shard 32 London Bridge Street London SE1 9SG London SE1 9SG (GB)

(54)	COMBINATIONS OF LOW, IMMUNE ENHANCING. DOSES OF MTOR INHIBITORS AND CARS