(19)
(11) EP 3 197 453 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
28.09.2022 Bulletin 2022/39

(45) Mention of the grant of the patent:
24.08.2022 Bulletin 2022/34

(21) Application number: 16707195.0

(22) Date of filing: 23.02.2016
(51) International Patent Classification (IPC): 
A61K 31/436(2006.01)
C07K 19/00(2006.01)
 C12N 15/62(2006.01)
C12N 15/85(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 31/436; C12N 15/62; C12N 9/6472; C07K 2319/70; C07K 14/705; C12N 9/1205; C12Y 304/22062; A61P 35/00; A61P 37/00; A61P 37/06; A61P 43/00; Y02A 50/30
 
C-Sets:
A61K 31/436, A61K 2300/00;
(86) International application number:
PCT/GB2016/050451
(87) International publication number:
WO 2016/135470 (01.09.2016 Gazette 2016/35)

(54)

CHIMERIC PROTEIN

CHIMÄRES PROTEIN

PROTÉINE CHIMÉRIQUE

(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 24.02.2015 GB 201503133

(43) Date of publication of application:
02.08.2017 Bulletin 2017/31

(60) Divisional application:
22191585.3

(73) Proprietor: Autolus Limited
London W12 7FP (GB)

(72) Inventors:
  • PULÉ, Martin
    London W12 7FP (GB)
  • TROWBRIDGE, Ryan
    London W127FP (GB)
  • HODGKIN, Edward
    London NW1 2BE (GB)

(74) Representative: D Young & Co LLP 
120 Holborn
London EC1N 2DY
London EC1N 2DY (GB)


(56) References cited: : 
WO-A1-96/41865
WO-A2-99/50425
US-A1- 2004 040 047
 WO-A1-2012/177927
WO-A2-2014/197638
US-B1- 6 916 917
   
  • ADRIAN FEGAN ET AL: "Chemically Controlled Protein Assembly: Techniques and Applications", CHEMICAL REVIEWS, vol. 110, no. 6, 9 June 2010 (2010-06-09), pages 3315-3336, XP055221903, US ISSN: 0009-2665, DOI: 10.1021/cr8002888
  • DI STASI ET AL.: "Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy", NEW ENGLAND JOURNAL OF MEDICINE, vol. 365, 2011, pages 1673-1683, XP002756622, cited in the application
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).