(19)
(11) EP 3 207 125 A1

(12)

(43) Date of publication:
23.08.2017 Bulletin 2017/34

(21) Application number: 15798556.5

(22) Date of filing: 13.10.2015
(51) International Patent Classification (IPC): 
C12N 5/074(2010.01)
C12N 5/0789(2010.01)
A61K 31/155(2006.01)
(86) International application number:
PCT/IB2015/057834
(87) International publication number:
WO 2016/059554 (21.04.2016 Gazette 2016/16)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA

(30) Priority: 17.10.2014 PL 40982514

(71) Applicant: Wroclawskie Centrum Badan EIT + SP Z O.O.
54-066 Wroclaw (PL)

(72) Inventors:
  • MARYCZ, Krzysztof
    51-188 Trzebnica (PL)
  • SMIESZEK, Agnieszka
    48-300 Nysa (PL)

(74) Representative: Witek, Rafal 
WTS Patent Attorneys Witek, Sniezko & Partners ul. Rudolfa Weigla 12
53-114 Wroclaw
53-114 Wroclaw (PL)

   


(54) PREPARATION FOR PLURIPOTENT VERY SMALL EMBRYONIC/EPIBLAST-LIKE STEM CELLS (VSELS) AND HEMATOPOIETIC STEM/PROGENITOR CELLS (HSPC) CD34+ MOBILISATION FROM BONE MARROW TO PERIPHERAL BLOOD AND THE USE OF METFORMIN (N,N-DIMETHYLBIGUANIDE)