(19)
(11) EP 3 209 415 A1

(12)

(43) Date of publication:
30.08.2017 Bulletin 2017/35

(21) Application number: 15787414.0

(22) Date of filing: 19.10.2015
(51) International Patent Classification (IPC): 
B01J 19/12(2006.01)
C07C 45/68(2006.01)
C07C 47/565(2006.01)
 C07C 45/67(2006.01)
C07C 45/81(2006.01)
C07C 47/575(2006.01)
(86) International application number:
PCT/US2015/056283
(87) International publication number:
WO 2016/064764 (28.04.2016 Gazette 2016/17)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA

(30) Priority: 20.10.2014 US 201462066009 P

(71) Applicant: United Therapeutics Corporation
Silver Spring, MD 20910 (US)

(72) Inventors:
  • BATRA, Hitesh
    Herndon, Virginia 20171 (US)
  • TULADHAR, Sudersan
    Silver Spring, Maryland 20904 (US)
  • WALSH, David A.
    Spotsylvania, Virginia 22551 (US)

(74) Representative: Hoffmann Eitle 
Patent- und Rechtsanwälte PartmbB Arabellastraße 30
81925 München
81925 München (DE)

   


(54) SYNTHESIS OF INTERMEDIATE FOR PRODUCING PROSTACYCLIN DERIVATIVES