(19)

(11)

EP 3 213 076 A1

(12)

(43) Date of publication: 06.09.2017 Bulletin 2017/36 (21) Application number: 15782207.3 (22) Date of filing: 06.10.2015

(51) International Patent Classification (IPC):  G01N 33/569(2006.01) C12N 15/62(2006.01) C07K 14/20(2006.01) (86) International application number: PCT/US2015/054303 (87) International publication number: WO 2016/057562 (14.04.2016 Gazette 2016/15)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA (30) Priority: 07.10.2014 US 201462060867 P 06.11.2014 US 201462076059 P (71) Applicant: The Research Foundation for The State University of New York Albany NY 12207 (US)	(72) Inventors: LUFT, Benjamin J. Riverhead, NY 11901 (US) BRUNO, John F. Ridge, NY 11961 (US) XU, Yun Stony Brook, NY 11790 (US) (74) Representative: Cahill, Susanne  PurdyLucey Intellectual Property 6/7 Harcourt Terrace Dublin 2 Dublin 2 (IE)