(19)
(11) EP 3 215 186 A2

(12)

(88) Date of publication A3:
25.08.2016

(43) Date of publication:
13.09.2017 Bulletin 2017/37

(21) Application number: 15856516.8

(22) Date of filing: 04.11.2015
(51) International Patent Classification (IPC): 
A61K 39/00(2006.01)
(86) International application number:
PCT/US2015/059104
(87) International publication number:
WO 2016/073647 (12.05.2016 Gazette 2016/19)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA MD

(30) Priority: 04.11.2014 US 201462075129 P

(71) Applicant: University of Southern California
Los Angeles, CA 90015 (US)

(72) Inventors:
  • LI, Wei
    Altadena, California 91001 (US)
  • WOODLEY, David
    Altadena, California 91001 (US)
  • CHEN, Mei
    Altadena, California 91001 (US)
  • SAHU, Divya
    San Diego, California 92126 (US)
  • DONG, Hangming
    Guangzhou Guangzhou 510515 (CN)
  • ZOU, Mengchen
    Guangzhou Guangzhou 510515 (CN)

(74) Representative: Hutter, Anton et al
Venner Shipley LLP 200 Aldersgate
London EC1A 4HD
London EC1A 4HD (GB)

   


(54) COMPOSITIONS AND METHODS FOR TREATING HIF-1alpha OVER-EXPRESSING CANCERS