(19)

(11)

EP 3 227 680 A1

(12)

(43) Date of publication: 11.10.2017 Bulletin 2017/41 (21) Application number: 15865346.9 (22) Date of filing: 04.12.2015

(51) International Patent Classification (IPC):  G01N 33/53(2006.01) G01N 33/543(2006.01) G01N 21/64(2006.01) G01N 30/72(2006.01) G01N 33/533(2006.01) G01N 33/68(2006.01) G01N 27/62(2006.01) A61K 31/55(2006.01) (86) International application number: PCT/US2015/063952 (87) International publication number: WO 2016/090228 (09.06.2016 Gazette 2016/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 05.12.2014 US 201462088118 P 23.01.2015 US 201562106863 P (71) Applicants: Myriad Genetics, Inc. Salt Lake City, UT 84108 (US) Kaldate, Rajesh Salt Lake City, UT 84108 (US)

(72) Inventor: KALDATE, Rajesh Salt Lake City, UT 84108 (US) (74) Representative: Gibson, Mark  Sagittarius IP Three Globeside Fieldhouse Lane Marlow, Buckinghamshire SL7 1HZ Marlow, Buckinghamshire SL7 1HZ (GB)