(19)

(11)

EP 3 247 330 A1

(12)

(43) Date of publication: 29.11.2017 Bulletin 2017/48 (21) Application number: 16706041.7 (22) Date of filing: 20.01.2016

(51) International Patent Classification (IPC):  A61K 9/00(2006.01) A61K 47/38(2006.01) A61K 31/198(2006.01) A61K 9/10(2006.01) A61K 31/195(2006.01) (86) International application number: PCT/US2016/014005 (87) International publication number: WO 2016/118556 (28.07.2016 Gazette 2016/30)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 20.01.2015 US 201562105565 P 30.12.2015 US 201562272922 P (71) Applicant: AbbVie Inc. North Chicago, IL 60064 (US)

(72) Inventors: CONJEEVARAM, Rajkumar Lake Bluff, Illinois 60044 (US) DEAC, Alexandru Skokie, Illinois 60076 (US) HUANG, Ye Gurnee, Illinois 60031 (US) MACKEY, Sean E. Grayslake, Illinois 60030 (US) MENGES, Randy A. Lake Villa, Illinois 60046 (US) ZIMMERMAN, Jayne B. Deerfield, Illinois 60606 (US) (74) Representative: Garner, Stephen et al Mathys & Squire LLP The Shard 32 London Bridge Street London SE1 9SG London SE1 9SG (GB)