(19)
(11) EP 3 248 543 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
21.02.2024 Bulletin 2024/08

(45) Mention of the grant of the patent:
06.12.2023 Bulletin 2023/49

(21) Application number: 16171060.3

(22) Date of filing: 24.05.2016
(51) International Patent Classification (IPC): 
A61B 5/055(2006.01)
 A61B 5/00(2006.01)
(52) Cooperative Patent Classification (CPC):
A61B 5/0042; A61B 5/055; A61B 5/1075; A61B 2576/026; G16H 30/40

(54)

APPARATUS AND METHOD FOR VISUALIZING TISSUE MACRO- AND MICROSTRUCTURE FOR PATHOLOGY EVALUATION IN MAGNETIC RESONANCE IMAGING

VORRICHTUNG UND VERFAHREN ZUR VISUALISIERUNG VON GEWEBEMAKRO- UND MIKROSTRUKTUR ZUR PATHOLOGIEBEURTEILUNG BEI DER MAGNETRESONANZBILDGEBUNG

APPAREIL ET PROCÉDÉ DE VISUALISATION DE MACRO- ET MICROSTRUCTURE DE TISSU POUR ÉVALUATION DE PATHOLOGIE DANS L'IMAGERIE PAR RÉSONANCE MAGNÉTIQUE

(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(43) Date of publication of application:
29.11.2017 Bulletin 2017/48

(73) Proprietors:
  • Siemens Healthineers AG
    91301 Forchheim (DE)
  • Centre Hospitalier Universitaire Vaudois
    1011 Lausanne (CH)

(72) Inventors:
  • BONNIER, Guillaume
    1023 Crissier (CH)
  • GRANZIERA, Cristina
    1020 Renens (CH)
  • KRÜGER, Gunnar
    Watertown, MA 02472 (US)
  • KOBER, Tobias
    1007 Lausanne (CH)

(74) Representative: Siemens Patent Attorneys 
Postfach 22 16 34
80506 München
80506 München (DE)


(56) References cited: : 
US-A1- 2009 252 391
 US-A1- 2014 341 471
   
  • LORIO, S. ET AL.: "Disentangling in vivo the effects of iron content and atrophy on the ageing human brain", NEUROLMAGE, vol. 103, 28 September 2014 (2014-09-28), pages 280-289, XP029093185,
  • DRAGANSKI, B ET AL.: "Regional specificity of MRI contrast parameter changes in normal ageing revealed by voxel-based quantification (VBQ)", NEUROLMAGE, vol. 55, no. 4, 28 January 2011 (2011-01-28), pages 1423-1434, XP028368088,
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).