(19)

(11)

EP 3 250 217 A1

(12)

(43) Date of publication: 06.12.2017 Bulletin 2017/49 (21) Application number: 16702517.0 (22) Date of filing: 28.01.2016

(51) International Patent Classification (IPC):  A61K 35/747(2015.01) C12R 1/225(2006.01) C12N 1/20(2006.01) (86) International application number: PCT/EP2016/051838 (87) International publication number: WO 2016/120405 (04.08.2016 Gazette 2016/31)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 30.01.2015 EP 15153271 10.07.2015 DE 102015008966 (71) Applicant: Technische Universität München 80333 München (DE)	(72) Inventors: BAUER, Johann 85737 Ismaning (DE) SCHWAIGER, Karin 85368 Moosburg (DE) (74) Representative: V.O.  P.O. Box 87930 Carnegieplein 5 2508 DH Den Haag 2508 DH Den Haag (NL)