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EP 3 253 796 A1

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(43) Date of publication: 13.12.2017 Bulletin 2017/50 (21) Application number: 16710325.8 (22) Date of filing: 02.02.2016

(51) International Patent Classification (IPC):  C07K 16/28(2006.01) A61K 39/395(2006.01) C07K 16/22(2006.01) A61P 37/02(2006.01) (86) International application number: PCT/IB2016/000182 (87) International publication number: WO 2016/125017 (11.08.2016 Gazette 2016/32)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 03.02.2015 US 201562111429 P (71) Applicants: Université Catholique de Louvain 1348 Louvain-la-Neuve (BE) Argen-X N.V. 4811 AH Breda (NL)	(72) Inventors: SAUNDERS, Michael B-1190 Brussels (BE) COULIE, Pierre B-1950 Kraainem (BE) LUCAS, Sophie B-3080 Tervuren (BE) DE BOECK, Gitte B-1840 Malderen (BE) VAN DE WONING, Sebastian B-9052 Gent (BE) DE HAARD, Hans NL-4436 NA Oudelande (NL) (74) Representative: Boult Wade Tennant  Verulam Gardens 70 Gray's Inn Road London WC1X 8BT London WC1X 8BT (GB)