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(11)

EP 3 256 161 A1

(12)

(43) Date of publication: 20.12.2017 Bulletin 2017/51 (21) Application number: 16705888.2 (22) Date of filing: 09.02.2016

(51) International Patent Classification (IPC):  A61K 39/395(2006.01) A61K 31/6615(2006.01) A61K 31/4196(2006.01) A61P 35/00(2006.01) (86) International application number: PCT/US2016/017075 (87) International publication number: WO 2016/130502 (18.08.2016 Gazette 2016/33)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 09.02.2015 US 201562113807 P (71) Applicant: Synta Pharmaceuticals Corp. Lexington, MA 02421 (US)	(72) Inventors: PROIA, David A. Newton, MA 02458 (US) RAO, Patricia E. Acton, MA 01720 (US) (74) Representative: Tostmann, Holger Carl  Wallinger Ricker Schlotter Tostmann Patent- und Rechtsanwälte Partnerschaft mbB Zweibrückenstrasse 5-7 80331 München 80331 München (DE)