| (84) |
Designated Contracting States: |
|
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL
NO PL PT RO RS SE SI SK SM TR |
| (30) |
Priority: |
23.02.2015 WO PCT/EP2015/000507
|
| (43) |
Date of publication of application: |
|
03.01.2018 Bulletin 2018/01 |
| (73) |
Proprietors: |
|
- Institut Curie
75005 Paris (FR)
- Centre National de la Recherche Scientifique
(C.N.R.S.)
75794 Paris Cedex 16 (FR)
- Institut Gustave Roussy
94805 Villejuif Cédex (FR)
- Assistance Publique-Hôpitaux de Paris (APHP)
75004 Paris (FR)
- Institut National de la Santé et de la Recherche
Médicale
75654 Paris 13 (FR)
- Université de Paris
75006 Paris (FR)
|
|
| (72) |
Inventors: |
|
- DEUTSCH, Eric
75004 Paris (FR)
- LUDGER, Johannes
92400 Courbevoie (FR)
- MONDINI, Michèle
75013 Paris (FR)
- NIZARD, Mevyn
94260 Fresnes (FR)
- PERFETTINI, Jean-Luc
77100 Meaux (FR)
- TARTOUR, Eric
75003 Paris (FR)
- TRAN, Thi
75018 Paris (FR)
|
| (74) |
Representative: Barbot, Willy |
|
Simodoro-ip
82, rue Sylvabelle
13006 Marseille
13006 Marseille (FR) |
| (56) |
References cited: :
EP-A1- 2 740 491
|
WO-A2-2012/177624
|
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| |
|
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- HAICHEUR N ET AL: "The B subunit of Shiga toxin fused to a tumor antigen elicits CTL
and targets dendritic cells to allow MHC class I-restricted presentation of peptides
derived from exogenous antigens", THE JOURNAL OF IMMUNOLOGY, THE AMERICAN ASSOCIATION
OF IMMUNOLOGISTS, US, vol. 165, no. 6, 15 September 2000 (2000-09-15), pages 3301-3308,
XP002228666, ISSN: 0022-1767 cited in the application
- REBECCA G. POMERANTZ ET AL: "The role of epidermal growth factor receptor in head
and neck squamous cell carcinoma", CURRENT ONCOLOGY REPORTS, vol. 5, no. 2, 1 April
2003 (2003-04-01), pages 140-146, XP055205530, ISSN: 1523-3790, DOI: 10.1007/s11912-003-0101-z
- R. HASSAN: "Tumor-Directed Radiation and the Immunotoxin SS1P in the Treatment of
Mesothelin-Expressing Tumor Xenografts", CLINICAL CANCER RESEARCH, vol. 12, no. 16,
15 August 2006 (2006-08-15), pages 4983-4988, XP055157621, ISSN: 1078-0432, DOI: 10.1158/1078-0432.CCR-06-0441
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