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(11)

EP 3 265 086 A1

(12)

(43) Date of publication: 10.01.2018 Bulletin 2018/02 (21) Application number: 16707535.7 (22) Date of filing: 25.02.2016

(51) International Patent Classification (IPC):  A61K 31/4412(2006.01) A61P 35/00(2006.01) A61K 31/4704(2006.01) (86) International application number: PCT/GB2016/050489 (87) International publication number: WO 2016/139455 (09.09.2016 Gazette 2016/36)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 04.03.2015 GB 201503668 (71) Applicant: UCL Business PLC London W1T 4TP (GB)	(72) Inventors: JALAN, Rajiv London W1T 4TP (GB) ANDREOLA, Fausto London W1T 4TP (GB) DI CHIARA, Francesco London W1T 4TP (GB) (74) Representative: Hutter, Anton et al Venner Shipley LLP 200 Aldersgate London EC1A 4HD London EC1A 4HD (GB)