(19)

(11)

EP 3 265 810 A1

(12)

(43) Date of publication: 10.01.2018 Bulletin 2018/02 (21) Application number: 16714094.6 (22) Date of filing: 06.03.2016

(51) International Patent Classification (IPC):  G01N 33/50(2006.01) G06F 17/10(2006.01) G01N 33/68(2006.01) (86) International application number: PCT/US2016/021101 (87) International publication number: WO 2016/144838 (15.09.2016 Gazette 2016/37)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 06.03.2015 US 201562129715 P 30.07.2015 US 201562198838 P (71) Applicant: Blanchette Rockefeller Neurosciences Institute Morgantown, WV 26505-3409 (US)	(72) Inventors: CHIRILA, Florin, V. Morgantown, WV 26505 (US) ALKON, Daniel, L. Chevy Chase, MD 20815 (US) (74) Representative: Finnegan Europe LLP  16 Old Bailey London EC4M 7EG London EC4M 7EG (GB)