(19)

(11)

EP 3 270 963 A2

(12)

(88) Date of publication A3: 23.03.2017 (43) Date of publication: 24.01.2018 Bulletin 2018/04 (21) Application number: 16765794.9 (22) Date of filing: 17.03.2016

(51) International Patent Classification (IPC):  A61K 39/39(2006.01) A61K 47/14(2017.01) A61K 47/26(2006.01) (86) International application number: PCT/US2016/022977 (87) International publication number: WO 2016/149558 (22.09.2016 Gazette 2016/38)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 17.03.2015 US 201514660523 18.03.2015 US 201562135092 P 15.07.2015 US 201514800003 (71) Applicant: Sequoia Sciences, Inc. St. Louis MO 63114 (US)	(72) Inventors: ELDRIDGE, Gary St. Louis, Missouri 63119 (US) MARTIN, Steven M. St. Louis, Missouri 63119 (US) (74) Representative: De Groote, Christophe et al Abyoo sprl Centre Monnet Avenue Jean Monnet, 1 1348 Louvain-la-Neuve 1348 Louvain-la-Neuve (BE)