(19)
(11) EP 3 273 975 A1

(12)

(43) Date of publication:
31.01.2018 Bulletin 2018/05

(21) Application number: 16769745.7

(22) Date of filing: 25.03.2016
(51) International Patent Classification (IPC): 
A61K 35/12(2015.01)
C12N 5/074(2010.01)
C12N 15/85(2006.01)
 A61P 35/00(2006.01)
C12N 15/09(2006.01)
(86) International application number:
PCT/US2016/024146
(87) International publication number:
WO 2016/154508 (29.09.2016 Gazette 2016/39)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA MD

(30) Priority: 26.03.2015 US 201562138684 P
26.03.2015 US 201562138969 P

(71) Applicant: The Trustees of The University of Pennsylvania
Philadelphia, PA 19104 (US)

(72) Inventor:
  • LOWENFELD, Lea
    Philadelphia, PA 19104 (US)

(74) Representative: Biggi, Cristina 
Bugnion S.p.A. Viale Lancetti 17
20158 Milano
20158 Milano (IT)

   


(54) IN VITRO ARTIFICIAL LYMPH NODE FOR SENSITIZATION AND EXPANSION OF T CELLS FOR THERAPY AND EPITOPE MAPPING