| (84) |
Designated Contracting States: |
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AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL
NO PL PT RO RS SE SI SK SM TR |
| (30) |
Priority: |
08.04.2015 US 201562144702 P
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| (43) |
Date of publication of application: |
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14.02.2018 Bulletin 2018/07 |
| (73) |
Proprietor: The United States of America, as represented by
the Secretary, Department of Health and Human
Services |
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Maryland 20892-7660 (US) |
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| (72) |
Inventors: |
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- VENDITTI, Charles, P.
Kensington, MD 20895 (US)
- PAVAN, William, J.
Derwood, MD 20855 (US)
- CHANDLER, Randy
Washington, DC 20009 (US)
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| (74) |
Representative: Huenges, Martin |
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Maiwald Patentanwalts- und
Rechtsanwaltsgesellschaft mbH
Elisenhof
Elisenstraße 3 80335 München 80335 München (DE) |
| (56) |
References cited: :
WO-A1-2009/043936 WO-A2-2012/061744
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WO-A1-2011/020118
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- C.A. PAUL ET AL: "Adenovirus expressing an NPC1-GFP fusion gene corrects neuronal
and nonneuronal defects associated with Niemann pick type C disease", JOURNAL OF NEUROSCIENCE
RESEARCH., vol. 81, no. 5, 1 September 2005 (2005-09-01), pages 706-719, XP055295101,
US ISSN: 0360-4012, DOI: 10.1002/jnr.20592
- Donald B Arnold ET AL: "A calcium responsive element that regulates expression of
two calcium binding proteins in Purkinje cells (transcription͞biolistic transfection͞Ca
2? responses͞calbindin͞calmodulin II) Communicated by", Neurobiology May,
1 August 1997 (1997-08-01), pages 8842-8847, XP055295089, Retrieved from the Internet:
URL:http://www.pnas.org/content/94/16/8842 .full.pdf [retrieved on 2016-08-11]
- T D BARBARA NGUYEN-VU ET AL: "Cerebellar Purkinje cell activity drives motor learning",
NATURE NEUROSCIENCE, vol. 16, no. 12, 27 October 2013 (2013-10-27), pages 1734-1736,
XP55295269, US ISSN: 1097-6256, DOI: 10.1038/nn.3576
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