(19)
(11) EP 3 288 458 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
18.12.2019 Bulletin 2019/51

(45) Mention of the grant of the patent:
13.11.2019 Bulletin 2019/46

(21) Application number: 16789365.0

(22) Date of filing: 02.05.2016
(51) International Patent Classification (IPC): 
A61B 5/1455(2006.01)
 G01N 33/68(2006.01)
(86) International application number:
PCT/IB2016/000658
(87) International publication number:
WO 2016/178083 (10.11.2016 Gazette 2016/45)

(54)

METHOD FOR MEASURING TEAR CONSTITUTENTS IN A TEAR SAMPLE

VERFAHREN ZUR MESSUNG DER TRÄNENBESTANDTEILE IN EINER FLÜSSIGPROBE

PROCÉDÉ DE MESURE DE CONSTITUANTS DE LARME DANS UN ÉCHANTILLON DE LARME

(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 01.05.2015 US 201562156093 P
01.05.2015 US 201562156079 P
01.05.2015 US 201562156072 P
01.05.2015 US 201562156087 P
14.01.2016 US 201662278814 P
14.01.2016 US 201662278805 P

(43) Date of publication of application:
07.03.2018 Bulletin 2018/10

(73) Proprietor: DiagnosTear, Ltd.
6158101 Tel Aviv (IL)

(72) Inventors:
  • SOMMER, Amos
    46344 Herzliya (IL)
  • FAKTOR, Ouriel
    46344 Herzliya (IL)
  • EILAT, Eran
    46344 Herzliya (IL)

(74) Representative: CMS Cameron McKenna Nabarro Olswang LLP 
Cannon Place 78 Cannon Street
London EC4N 6AF
London EC4N 6AF (GB)


(56) References cited: : 
US-A1- 2014 314 715
 US-A1- 2014 357 971
   
  • BRON ET AL: "Methodologies to diagnose and monitor dry eye disease: Report of the Diagnostic Methodology Subcommittee of the International Dry Eye Work Shop (2007", THE OCULAR SURFACE, vol. 5, no. 2, 1 January 2007 (2007-01-01) , pages 108-152, XP055398885,
  • LI ET AL.: 'Quantification of tear proteins and sPLA2-IIa alteration in patients with allergic conjunctivitis' MOLECULAR VISION vol. 16, 14 October 2010, pages 2084 - 2091, XP055338272
  • SRINIVASAN ET AL.: 'iTRAQ Quantitative Proteomics in the Analysis of Tears in Dry Eye Patients' IOVS vol. 53, no. 8, July 2012, pages 5052 - 5059, XP055338275
  • VERSURA ET AL.: 'Diagnostic performance of a tear protein panel in early dry eye' MOLECULAR VISION; vol. 19, 06 June 2013, pages 1247 - 1257, XP055338276
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).