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EP 3 288 636 A1

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(43) Date of publication: 07.03.2018 Bulletin 2018/10 (21) Application number: 15891259.2 (22) Date of filing: 01.05.2015

(51) International Patent Classification (IPC):  A61P 11/02(2006.01) A61K 47/30(2006.01) A61K 31/137(2006.01) A61K 9/70(2006.01) (86) International application number: PCT/IB2015/001451 (87) International publication number: WO 2016/178053 (10.11.2016 Gazette 2016/45)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA (71) Applicant: Topitech Pharma Israel Ltd. 4634401 Herzliya (IL)	(72) Inventors: Lozinsky, Evgenia 8465138 Beer-Sheva (IL) Eilat, Eran 4634401 Herzliya (IL) (74) Representative: Trinks, Ole  Meissner Bolte Patentanwälte Rechtsanwälte Partnerschaft mbB Widenmayerstraße 47 80538 München 80538 München (DE)