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(11)

EP 3 294 328 A1

(12)

(43) Date of publication: 21.03.2018 Bulletin 2018/12 (21) Application number: 16793285.4 (22) Date of filing: 06.05.2016

(51) International Patent Classification (IPC):  A61K 39/00(2006.01) A61K 38/04(2006.01) A61K 39/42(2006.01) (86) International application number: PCT/US2016/031364 (87) International publication number: WO 2016/182957 (17.11.2016 Gazette 2016/46)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 08.05.2015 US 201562158735 P 27.07.2015 US 201562197480 P (71) Applicant: Eureka Therapeutics, Inc. Emeryville, CA 94608 (US)	(72) Inventors: LIU, Cheng Emeryville, California 94608 (US) LIU, Hong El Sobrante, CA 94803 (US) WANG, Pei Union City, CA 94587 (US) CHAN, Vivien, Wai-Fan Emeryville, CA 94608 (US) (74) Representative: Carpmaels & Ransford LLP  One Southampton Row London WC1B 5HA London WC1B 5HA (GB)