(19)
(11) EP 3 296 309 A8

(12) CORRECTED EUROPEAN PATENT APPLICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 A1)

(48) Corrigendum issued on:
06.06.2018 Bulletin 2018/23

(43) Date of publication:
21.03.2018 Bulletin 2018/12

(21) Application number: 17178121.4

(22) Date of filing: 20.06.2013
(27) Previously filed application:
 20.06.2013 EP 13729782
(51) International Patent Classification (IPC): 
C07H 15/04(2006.01)
A61P 31/00(2006.01)
 A61K 31/7032(2006.01)
A61P 35/00(2006.01)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 28.06.2012 US 201261665730 P

(62) Application number of the earlier application in accordance with Art. 76 EPC:
13729782.6 / 2877480

(71) Applicant: Universiteit Gent
9000 Gent (BE)

(72) Inventors:
  • ELEWAUT, Dirk
    9070 Heusden (BE)
  • PAUWELS, Nora
    9030 Mariakerke (BE)
  • ASPESLAGH, Sandrine
    8000 Brugge (BE)
  • VAN CALENBERGH, Serge
    9840 De Pinte (BE)

(74) Representative: Office Kirkpatrick 
Avenue Wolfers, 32
1310 La Hulpe
1310 La Hulpe (BE)

 
Remarks:
This application was filed on 27.06.2017 as a divisional application to the application mentioned under INID code 62.
 


(54) GALACTOPYRANOSYL DERIVATIVES USEFUL AS MEDICAMENTS


(57) This invention relates to carbamate-containing or thiocarbamate-containing galacto-pyranosyl compounds useful as therapeutic agents and being represented by the structural formula (II), wherein: X is O or S, R is selected from the group consisting of C1-8 alkyl, C3-10 cycloalkyl, aryl-C1-4 alkyl, heterocyclyl-C1-4 alkyl, cycloalkyl-C1-4 alkyl, aryl and heterocyclyl, wherein R is optionally substituted with one or more R9; R2, R3, R4, R6 and R7 are independently selected from the group consisting of hydroxyl and protected hydroxyl groups; R5 is selected from the group consisting C6-30 alkyl and arylalkyl; R8 is C6-30 alkyl; and each R9 is independently selected from the group consisting of halogen, hydroxy, trifluoromethyl, trifluoromethoxy, C1-8 alkoxy, C1-6 alkyl, cyano, methylthio, phenyl, phenoxy, chloromethyl, dichloromethyl, chloro-difluoromethyl, acetyl, nitro, benzyl, heterocyclyl and di-C1-4 alkyl-amino, or a pharmaceutically acceptable salt thereof.