(84) |
Designated Contracting States: |
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AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL
NO PL PT RO RS SE SI SK SM TR |
(30) |
Priority: |
18.05.2015 US 201562163282 P 11.12.2015 US 201562266450 P
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(43) |
Date of publication of application: |
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28.03.2018 Bulletin 2018/13 |
(60) |
Divisional application: |
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20216691.4 |
(73) |
Proprietor: AB Initio Biotherapeutics, Inc. |
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San Diego, CA 92121 (US) |
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(72) |
Inventors: |
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- RING, Aaron Michael
Palo Alto, California 94306 (US)
- MAUTE, Roy Louis
San Francisco, California 94103 (US)
- KRUSE, Andrew Curtis
Roslindale, Massachusetts 02131 (US)
- MANGLIK, Aashish
Menlo Park, California 94025 (US)
- LIN, Kenneth S.
Los Altos, California 94023 (US)
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(74) |
Representative: Mewburn Ellis LLP |
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Aurora Building
Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB) |
(56) |
References cited: :
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10.1111/j.1476-5381.2012.02099.x
- GARY BROOKE ET AL: "Human Lymphocytes Interact Directly with CD47 Through a Novel
Member of the Signal Regulatory Protein (SIRP) Family", THE JOURNAL OF IMMUNO, THE
AMERICAN ASSOCIATION OF IMMUNOLOGISTS, US, vol. 173, no. 4, 15 August 2004 (2004-08-15),
pages 2562-2570, XP008138739, ISSN: 0022-1767
- JOANNE E NETTLESHIP ET AL: "Crystal structure of signal regulatory protein gamma (SIRP[gamma])
in complex with an antibody Fab frag", BMC STRUCTURAL BIOLOGY, BIOMED CENTRAL LTD.,
LONDON, GB, vol. 13, no. 1, 4 July 2013 (2013-07-04), page 13, XP021156553, ISSN:
1472-6807, DOI: 10.1186/1472-6807-13-13
- HATHERLEY, D ET AL.: 'Paired Receptor Specificity Explained by Structures of Signal
Regulatory Proteins Alone and Complexed with CD 47.' MOLECULAR CELL . vol. 31, no.
2, 25 July 2008, pages 266 - 277, XP055175089
- LEE, WY ET AL.: 'Novel Structural Determinants on SIRP alpha that Mediate Binding
to CD 47.' THE JOURNAL OF IMMUNOLOGY vol. 179, no. 11, 01 December 2007, pages 7741
- 7750, XP055081468
- STEFANIDAKIS, M ET AL.: 'Endothelial CD 47 Interaction with SIRP gamma is Required
for Human T- cell Transendothelial Migration Under Shear Flow Conditions In Vitro.'
BLOOD vol. 112, no. 4, 04 June 2008, pages 1280 - 1289, XP055331545
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