HALOGENATED SALICYLANILIDES FOR TREATING CLOSTRIDIUM INFECTIONS

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EP 3 302 492 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	28.04.2021 Bulletin 2021/17

(45)	Mention of the grant of the patent:
	17.03.2021 Bulletin 2021/11

(21)	Application number: 16725530.6

(22)	Date of filing: 27.05.2016

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International Patent Classification (IPC):

A61K 31/609^(2006.01)
A61P 31/04^(2006.01)

A61K 31/612^(2006.01)

(86)	International application number:
	PCT/EP2016/061968

(87)	International publication number:
	WO 2016/193136 (08.12.2016 Gazette 2016/49)

(54)	HALOGENATED SALICYLANILIDES FOR TREATING CLOSTRIDIUM INFECTIONS HALOGENIERTE SALICYLANILIDE ZUR BEHANDLUNG VON CLOSTRIDIUM-INFEKTIONEN SALICYLANILIDES HALOGÉNÉS POUR LE TRAITEMENT DES INFECTIONS PAR CLOSTRIDIUM

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

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Priority:

29.05.2015 GB 201509326

(43)	Date of publication of application:
	11.04.2018 Bulletin 2018/15

(73)	Proprietor: UNION therapeutics A/S
	2900 Hellerup (DK)

(72)	Inventors:
	SOMMER, Morten, Otto, Alexander 2830 Virum (DK) TOFT-KEHLER, Rasmus, Vendler 2100 København Ø (DK) SIMON, Daniel, Jean, Jacques 56520 Guidel (FR)

(74)	Representative: HGF
	1 City Walk Leeds LS11 9DX Leeds LS11 9DX (GB)

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References cited: :

WO-A1-2014/125075

WO-A2-2010/005836

PAUK KAREL ET AL: "New derivatives of salicylamides: Preparation and antimicrobial activity against various bacterial species", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, no. 21, 24 August 2013 (2013-08-24), pages 6574-6581, XP028732732, ISSN: 0968-0896, DOI: 10.1016/J.BMC.2013.08.029
RAJMOHAN RAJAMUTHIAH ET AL: "Repurposing Salicylanilide Anthelmintic Drugs to Combat Drug Resistant Staphylococcus aureus", PLOS ONE, vol. 10, no. 4, 21 April 2015 (2015-04-21) , page e0124595, XP055221148, DOI: 10.1371/journal.pone.0124595
NATALYA YUTIN ET AL: "A genomic update on clostridial phylogeny: Gram-negative spore formers and other misplaced clostridia", ENVIRONMENTAL MICROBIOLOGY, 9 July 2013 (2013-07-09), pages n/a-n/a, XP055340305, GB ISSN: 1462-2912, DOI: 10.1111/1462-2920.12173
Anonymous: "UK Standards for microbiology investigations - Identification of clostridium species", , 21 January 2015 (2015-01-21), XP055652860, Retrieved from the Internet: URL:https://assets.publishing.service.gov. uk/government/uploads/system/uploads/attac hment_data/file/504183/ID_8i4.1.pdf [retrieved on 2019-12-13]

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).