(19)

(11)

EP 3 303 367 A1

(12)

(43) Date of publication: 11.04.2018 Bulletin 2018/15 (21) Application number: 16808232.9 (22) Date of filing: 08.06.2016

(51) International Patent Classification (IPC):  C07K 14/00(2006.01) G01N 33/53(2006.01) C07K 7/00(2006.01) (86) International application number: PCT/US2016/036531 (87) International publication number: WO 2016/201007 (15.12.2016 Gazette 2016/50)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 08.06.2015 US 201562172669 P 28.08.2015 US 201562211603 P (71) Applicant: New York University New York City, NY 10012 (US)	(72) Inventors: ARORA, Paramjit, S. Cold Spring Harbor, NY 11724 (US) WUO, Michael, G. Brooklyn, NY 11205 (US) (74) Representative: Adamson Jones  BioCity Nottingham Pennyfoot Street Nottingham NG1 1GF Nottingham NG1 1GF (GB)