ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESILTLVFIROMKCYALTRBGCZEEHUPLSK..HRIS..MTNORS..SM..................JBDM Ver 2.0.16 (1th of February 2022) - 2999001/0The file contains technical information submitted after the application was filed and not included in this specification3318632CORRECTED EUROPEAN PATENT SPECIFICATIONB8B120221214W173deBibliographieenBibliographyfrBibliographieEP16818051.1201606302017122720191129jaenen201513303320150701JP2022121420225020180509201819202210262022432022051620221214202250C12N 15/09 20060101AFI20181207BHEP C12N 5/09 20100101ALI20181207BHEP G01N 33/53 20060101ALI20181207BHEP G01N 33/574 20060101ALI20181207BHEP C12Q 1/6886 20180101ALI20181207BHEP C12N 15/09 20130101 LI20170126BHEP G01N 33/53 20130101 LI20170126BHEP G01N 33/574 20130101 LI20170126BHEP C12Q 1/6886 20130101 FI20221014BHEP C12Q2600/158 20130101 LA20181203BHEP deMARKER DER HETEROGENITÄT VON KREBSGEWEBE UND VERWENDUNG DAVONenMARKER FOR HETEROGENEITY OF CANCER TISSUE, AND USE THEREOFfrMARQUEUR DE L'HOMOGÉNÉITÉ D'UN TISSU CANCÉREUX ET UTILISATION DUDIT MARQUEURWO-A1-2006/053442WO-A1-2010/064702WO-A1-2013/116144WO-A1-2014/144804CN-A- 101 993 944JP-A- 2007 527 220JP-A- 2009 513 161JP-A- 2012 525 159JP-A- 2013 507 987US-A1- 2014 100 121N. NAVIN ET AL: "Inferring tumor progression from genomic heterogeneity", GENOME RESEARCH, vol. 20, no. 1, 1 January 2010 (2010-01-01), pages 68-80, XP055210315, ISSN: 1088-9051, DOI: 10.1101/gr.099622.109LUCIANO G MARTELOTTO ET AL: "Breast cancer intra-tumor heterogeneity", BREAST CANCER RESEARCH, CURRENT MEDICINE GROUP LTD, GB, vol. 16, no. 3, 20 May 2014 (2014-05-20), page 210, XP021203826, ISSN: 1465-5411, DOI: 10.1186/BCR3658YANG, X. ET AL.: 'Microcirulatory fraction (MCF1) as a potential imaging marker for tumor heterogeneity in breast cancer.' MAGNETIC RESONANCE IMAGING vol. 30, no. 8, October 2012, ISSN 1541-2016 pages 1059 - 1067, XP055342304YIP, C. ET AL.: 'Primary esophageal cancer: heterogeneity as potential prognostic biomarker in patients treated with definitive chemotherapy and radiation therapy.' RADIOLOGY vol. 270, no. 1, January 2014, ISSN 0033-8419 pages 141 - 148, XP05534230620181213SAYA, Hideyukic/o Keio University School of Medicine 35, Shinanomachi Shinjuku-kuTokyo 160-8582JPARIMA, Yoshimic/o Keio University School of Medicine 35, Shinanomachi Shinjuku-kuTokyo 160-8582JPSEMBA, Takashic/o Keio University School of Medicine 35, Shinanomachi Shinjuku-kuTokyo 160-8582JPFujita Academy101970782837-20 PCTEP1-98, Dengakugakubo Kutsukake-choToyoake-shi, Aichi 470-1192JPSchnappauf, Georg101384397ZSP Patentanwälte PartG mbB Hansastraße 3280686 MünchenDEALATBEBGCHCYCZDEDKEEESFIFRGBGRHRHUIEISITLILTLULVMCMKMTNLNOPLPTRORSSESISKSMTRJP201606952920160630jaWO201700294320170105201701