(19)
(11) EP 3 320 340 A1

(12)

(43) Date of publication:
16.05.2018 Bulletin 2018/20

(21) Application number: 16735628.6

(22) Date of filing: 01.07.2016
(51) International Patent Classification (IPC): 
G01N 33/53(2006.01)
G01N 33/543(2006.01)
 G01N 27/327(2006.01)
(86) International application number:
PCT/EP2016/065564
(87) International publication number:
WO 2017/005645 (12.01.2017 Gazette 2017/02)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA MD

(30) Priority: 06.07.2015 US 201514792569

(71) Applicant: Robert Bosch GmbH
70442 Stuttgart (DE)

(72) Inventors:
  • GANGADHARAN, Rajan
    Santa Clara, California 95050 (US)
  • VERMA, Piyush
    Sunnyvale, California 94087 (US)
  • JOHNSON, Christopher
    San Carlos, CA 94070 (US)
  • KAVUSI, Sam
    Menlo Park, California 94025 (US)
  • LAU, Aldrich
    Palo Alto, California 94301 (US)

(74) Representative: Isarpatent 
Patent- und Rechtsanwälte Behnisch Barth Charles Hassa Peckmann & Partner mbB Friedrichstrasse 31
80801 München
80801 München (DE)

   


(54) METHODS FOR GENERATING pH/IONIC CONCENTRATION GRADIENT NEAR ELECTRODE SURFACES FOR MODULATING BIOMOLECULAR INTERACTIONS