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(11)

EP 3 328 306 A1

(12)

(43) Date of publication: 06.06.2018 Bulletin 2018/23 (21) Application number: 16747566.4 (22) Date of filing: 27.07.2016

(51) International Patent Classification (IPC):  A61B 34/30(2016.01) A61B 34/00(2016.01) A61B 17/62(2006.01) A61B 34/32(2016.01) A61B 17/64(2006.01) (86) International application number: PCT/GB2016/052294 (87) International publication number: WO 2017/017443 (02.02.2017 Gazette 2017/05)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 30.07.2015 GB 201513436 (71) Applicant: University of The West of England, Bristol Bristol BS16 1QY (GB)	(72) Inventors: DOGRAMADZI, Sanja Bristol BS16 1QY (GB) GEORGILAS, Ioannis Bristol BS16 1QY (GB) DAGNINO, Giulio Bristol BS16 1QY (GB) (74) Representative: Mears, Andrew David  Withers & Rogers LLP 4 More London Riverside London SE1 2AU London SE1 2AU (GB)