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EP 3 328 435 A1

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(43) Date of publication: 06.06.2018 Bulletin 2018/23 (21) Application number: 16830851.8 (22) Date of filing: 28.07.2016

(51) International Patent Classification (IPC):  A61K 47/30(2006.01) A61K 47/34(2017.01) A61K 31/337(2006.01) A61K 47/32(2006.01) A61K 9/107(2006.01) A61K 31/122(2006.01) (86) International application number: PCT/KR2016/008267 (87) International publication number: WO 2017/018818 (02.02.2017 Gazette 2017/05)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 28.07.2015 KR 20150106627 (71) Applicant: Samyang Biopharmaceuticals Corporation Seoul 03129 (KR)

(72) Inventors: KIM, Bong Oh Daejeon 35212 (KR) KYUNG, Kyu Jin Yangju-si Gyeonggi-do 11485 (KR) KIM, Ji Yeong Hanam-si Gyeonggi-do 12911 (KR) KIM, Hye Rim Daejeon 34667 (KR) MIN, Bum Chan Daejeon 34166 (KR) YOON, Yoo Jeong Changwon-si Gyeongsangnam-do 51773 (KR) SEO, Min Hyo Daejeon 35245 (KR) YI, Yil Woong Daejeon 34034 (KR) (74) Representative: Schrell, Andreas et al Gleiss Große Schrell und Partner mbB Patentanwälte Rechtsanwälte Leitzstrasse 45 70469 Stuttgart 70469 Stuttgart (DE)