ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESILTLVFIROMKCYALTRBGCZEEHUPLSK..HRIS..MTNORS..SM..................*JBDM Ver 2.0.15 (20th of December) - 2999001/03334462CORRECTED EUROPEAN PATENT SPECIFICATIONB8B120220420W173deBibliographieenBibliographyfrBibliographieEP16837634.1201608152018031420200406enenen201562205121 P20150814US2022042020221620180620201825202201192022032021081020220420202216A61K 47/50 20170101AFI20190703BHEP A61K 47/06 20060101ALI20190703BHEP A61K 31/5383 20060101ALI20190703BHEP A61K 31/426 20060101ALI20190703BHEP A61P 35/00 20060101ALI20190703BHEP A61K 47/68 20170101ALI20190703BHEP C07K 16/32 20060101ALI20190703BHEP A61K 47/6803 20170801 FI20181203BHEP A61K 47/6855 20170801 LI20181203BHEP A61K 47/6869 20170801 LI20181203BHEP A61K 47/6889 20170801 LI20180621BHEP C07K 16/32 20130101 LA20180301BHEP A61P 35/00 20180101 LI20180621BHEP deKOVALENTE LINKER IN ANTIKÖRPER-WIRKSTOFF-KONJUGATEN UND VERFAHREN ZUR HERSTELLUNG UND VERWENDUNG DAVONenCOVALENT LINKERS IN ANTIBODY-DRUG CONJUGATES AND METHODS OF MAKING AND USING THE SAMEfrLIEURS COVALENTS DANS DES CONJUGUÉS ANTICORPS-MÉDICAMENT ET LEURS PROCÉDÉS DE PRODUCTION ET D'UTILISATIONWO-A1-2013/085925WO-A1-2013/085925WO-A1-2015/004400WO-A2-2015/187596WO-A2-2016/064749CN-A- 103 933 575CN-A- 103 933 575US-A1- 2003 215 395YAO, X. ET AL.: 'A novel humanized anti-HER2 antibody conjugated with MMAE exerts potent anti-tumor activity' BREAST CANCER RESEARCH AND TREATMENT vol. 153, no. 1, 08 August 2015, pages 123 - 133, XP055370764QIN, M. ET AL.: 'Click conjugation of peptide to hydrogel nanoparticles for tumor-targeted drug delivery' BIOMACROMOLECULES vol. 15, no. 10, 13 October 2014, pages 3728 - 3734, XP055370767J. Guenther ET AL: "Synthesis, Immobilization, MAS and HR-MAS NMR of a New Chelate Phosphine Linker System, and Catalysis by Rhodium Adducts Thereof", Advanced Synthesis & Catalysis, vol. 353, no. 2-3, 11 February 2011 (2011-02-11), pages 443-460, XP055681607, DE ISSN: 1615-4150, DOI: 10.1002/adsc.2010005852019070921206552.8398143320211104HUANG, Chang Jiang11822 Exposition Blvd.Los Angeles, CA 90064USFANG, Jianmin4112 Amaranta Ave.Palo Alto, CA 94306USYE, Hui15 Fen Tai Shan Road Economic Development Zone YantaiShandong 264006CNZHANG, Lezhi57 Zhang Jia Zhuang Village Da Ji Jia Street Economic Development Zone YantaiShandong 264006CNRemeGen Biosciences, Inc.101940201ICHEM-951/EP4059 Clipper CourtFremont, CA 94538USIcosa10121833783 avenue Denfert-Rochereau75014 ParisFRALATBEBGCHCYCZDEDKEEESFIFRGBGRHRHUIEISITLILTLULVMCMKMTNLNOPLPTRORSSESISKSMTRUS201604698720160815enWO20170310342017022320170820170330000000